Carbon 60 and Mitochondrial energy
By absorbing nearby acid the carbon 60 molecule known as C60 is then attracted to the mitochondria and carries the protons superoxide (SOD) acceptors to prevent the very source of damage from the electron transport chain / krebs cycle / energy production cycle, this is seen as the key to the improvements in sports performance, addressing fatigue and the anti ageing properties of C60.
The proposed mechanism indicates that C60 has the ability to acquire positive charge by absorbing protons (positively charged hydrogen atoms) and this complex could enter the mitochondria, leading to a decrease in reactive oxygen species production.
Many experimenters with C60 notice this increase in energy, performance and mental clarity initially but for some they plateau this could be because it becomes the ‘new normal’. Others find that they get even better results adding other nutrients that further support the optimal function of the mitchondria such as Carnitine, CoQ10, PQQ, Lipoic Acid, NAD, Alpha Ketoglutarate & Magnesium.
Additional nutrients for giving fatigue the nudge
Other nutrients that can help support cellular energy production and give your energy levels a boost are PQQ, malic acid, carnitine, coenzyme Q10, lipoic acid, essential fatty acids and B vitamins.
PQQ is a novel biofactor, known to influence multiple cellular pathways, including the production of nerve growth factor (NGF). PQQ has diverse benefit for mitochondrial function, and has been shown to attenuate mitochondrial oxidative stress as well as to stimulate mitochondrial biogenesis. It also has neuroprotective properties including protection against glutamate induced toxicity, a pathway common in many neurodegenerative diseases. BioPQQ is considered a novel cofactor with antioxidant and B vitamin-like activity. BioPQQ® is naturally fermented to enhance absorption.
Malic Acid: This nutrient is a key component in our cellular energy production pathways and can therefore help boost energy production. It may also increase stamina.
Carnitine, an important nutrient, plays a role in fat metabolism and energy production. It transports dietary fats directly into the mitochondria to be broken down and burnt as fuel for energy production.
Coenzyme Q10 is a vitamin-like compound that is essential for energy production, as it enhances cellular energy production and is also a powerful antioxidant.
Lipoic Acid is important for the transport and conversion of carbohydrates into energy. It is also a powerful antioxidant.
Omega 3 essential fatty acids: Fish oil especially combined with Evening Primrose oil is vital for the integrity and stability of every cell in our body. Omega-3 oils stimulate energy production and help lower stress levels.
B Vitamins are essential, especially when under stress. All the B vitamins are vital for the Krebs cycle to produce energy. A combination that includes magnesium with B vitamins is likely to help you feel energised and able to enjoy life.
Activated B3 | NAD
NAD is a water soluble molecule that plays a critical role in many energetic processes, particularly in glycolysis, in the Krebs cycle and electron chain transport. Without NAD, the cell would produce insufficient energy to maintain normal function. Nicotinamide adenine dinucleotide, in its reduced form (abbreviated is NADH), may be viewed as an energy substitute. One mole of NADH will form 3 moles of ATP. This, then provides the cell with additional energy. The more NADH a cell has available, the more energy it can produce.
Marvellous magnesium – an essential mineral for fatigue
Magnesium, an essential mineral, is used in over 300 chemical processes in your body. It also plays a key role in the production of energy.
Many of us are low in magnesium due to dietary insufficiencies. Supplementing your diet with a pleasant-tasting magnesium powder may help with your energy production. A magnesium supplement may also assist with cramped, tense or twitching muscles. Adequate magnesium levels may also help us to cope with stress. It is great to take magnesium before bed as it also acts as a relaxant and alkalizing agent for a good nights sleep.
Testing the Mitochondria and More
GENOVA Metabolic Analysis Profile (Organic Acids) available at Naturopathic Care
The Metabolic Analysis Profile is a nutritional test that assesses urine metabolites in order to evaluate four critical areas of metabolism: gastrointestinal function, cellular and mitochondrial energy production, neurotransmitter processing, and amino acid/organic acid balance as influenced by vitamin/mineral cofactors. Results can be used to address chronic systemic complaints ranging from chronic fatigue and mood disorders to headache, muscular/joint pain, and digestive problems.
The Metabolic Analysis Profile is a nutritional test using a urinary assessment of 46 key organic acids grouped according to their primary roles in the following four central areas of metabolism.
Gastrointestinal Function This profile measures eight markers that can reveal malabsorption and dysbiosis. These imbalances can be addressed to improve gut health and to help prevent or alleviate: chronic digestive problems, common causes of nutritional deficiency, yeast overgrowth, cognitive impairment, gastrointestinal distress and degenerative conditions.
Energy Production This profile assesses metabolites that serve as important intermediates in the citric acid (Krebs) cycle. This cycle supplies the body with its primary energy needs, converting 90% of food energy into cellular energy. This panel also includes:•Carbohydrate metabolites that can signal impaired glucose metabolism•Markers that help evaluate the breakdown of fats and production of cholesterol•A marker measuring the production of coenzyme Q10 Imbalances of cellular energy metabolites are linked with chronic fatigue, accelerated cell breakdown and unhealthy aging.
Neurotransmitter Metabolites These serve as important diagnostic indicators of abnormal metabolism that can underline many key aspects of neuropsychiatric function. These markers are urinary metabolites of powerful neurotransmitters that act on the central nervous system, including Adrenaline, Dopamine and Serotonin. These substances can profoundly influence patterns of stress response, emotional well-being, cognition and sleep.